Comparison of immunohistochemistry and virus cultivation for detection of viral haemorrhagic septicaemia virus in experimentally infected rainbow trout Oncorhynchus mykiss

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Comparison of immunohistochemistry and virus cultivation for detection of viral haemorrhagic septicaemia virus in experimentally infected rainbow trout Oncorhynchus mykiss

lmmunohistochem~stry and virus isolation were compared for their ability to detect viral haemorrhagic septicaemia vlrus (VHS) in experimentally ~nfected ralnbow trout Oncorhynchus mykiss. The f ~ s h were divided into 3 g]-oups ( I to I l l ) , and infected, respectively, by bath challenge w ~ t h 102, 103 ', and 10"CID50 ml-l water of a VHS virus strain serologically sllnilar to reference stra...

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Cell-mediated cytotoxicity in rainbow trout, Oncorhynchus mykiss, infected with viral haemorrhagic septicaemia virus.

Mammalian cytotoxic T cells as part of the adaptive immune system recognize virus-infected target cells by binding of their T-cell receptors (TCR) to classical MHC class I molecules loaded with viral peptides. Our previous studies have shown that the allele of the single dominant polymorphic classical MHC class I locus Onmy-UBA is identical in the rainbow trout clone C25 and in the permanent ra...

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The risk associated with vertical transmission of viral haemorrhagic septicaemia virus (VHSV) in rainbow trout (Oncorhynchus mykiss) eggs

To assess the risk posed by vertical transmission of viral haemorrhagic septicaemia virus, VHSV, in rainbow trout ova, an experimental challenge study was conducted. Prior to the fertilisation process samples of milt and/or ova were infected with VHSV. Virus was not detected from either the fertilised ova or hatched fry. These results indicate that the risk associated with VHSV vertical transmi...

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In vitro susceptibility of rainbow trout fin cells to viral haemorrhagic septicaemia virus

Cells isolated from rainbow trout fins Oncorhynchus mykiss, Walbaum were propagated and subcultured a s fibroblast-like. Viral haemorrhagic septicaemia virus (VHSV) replicated in the cultured fin cells as demonstrated by fin cell lysis, posihve immunofluorescence with polyclonal antiVHSV, and Increase in titre as measured by either infection of f ~ s h cell lines or by sandwich ELISA with anti-...

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Spectrophotometric method for titration of trout interferon, and its application to rainbow trout fry experimentally infected with viral haemorrhagic septicaemia virus

The activity of a reference preparation of rainbow trout circulating interferon (IFN), induced by experimental infection of fish with viral haemorrhagic septicaemia virus, was detected on the basis of its non-specific protective effect for RTG-2 cells, grown in microplates and challenged with infectious pancreatic necrosis virus. The IFN was titrated by spectrophotometric assessment of the abso...

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ژورنال

عنوان ژورنال: Diseases of Aquatic Organisms

سال: 1994

ISSN: 0177-5103,1616-1580

DOI: 10.3354/dao020101